Oral pills are often the first line of treatment for erectile dysfunction. For most men who have trouble maintaining an erection good enough for sex (erectile dysfunction), these drugs work well and have few side effects.

Sildenafil (Viagra), vardenafil (Levitra, Staxin), tadalafil (Cialis), and avanafil (Stendra) are oral medications that reverse erectile dysfunction by increasing the effects of nitric oxide.

This increases blood flow and helps achieve an erection in response to sexual stimulation.

Differences between oral medications (ED Pills)

They work the same, but each oral drug has a slightly different chemical composition. These small differences affect the action of each drug, including drug effectiveness, wear rate, and potential side effects.

Your doctor will consider these factors as well as possible interactions with other conditions you have and other medications you are taking.

Sildenafil (Viagra). This medicine is most effective when taken on an empty stomach 1 hour before sexual intercourse. If you have mild to moderate erectile dysfunction, it is effective for 4-5 hours or more.

Vardenafil (Levitra, Staxin). This medicine is also most effective when taken 1 hour before intercourse and can be taken with or without food. A high-fat diet can prevent its rapid absorption.

Vardenafil is effective for 4-5 hours or more with mild to moderate erectile dysfunction. New forms of medicines that dissolve on the tongue can work faster than ingested tablets.

Tadalafil (Cialis). This medicine should be taken approximately 1-2 hours before sexual intercourse, with or without food. Valid up to 36 hours. It can be taken in small doses per day or in large doses as needed.

Avanafil (Stendra). This medicine should be taken 30 minutes before sexual intercourse with or without food, depending on the dose. Lasts up to 6 hours.

Because these drugs are equally effective, the American College of Physicians recommends choosing based on your preferences, such as cost, ease of use, duration of the drug’s effect, and side effects.

There are generic versions of Sildenafil, Vardenafil and Tadalafil available in the market.

CENFORCE (Sildenafil -Viagra)

Cenforce 200 Sildenafil is commonly used in the treatment of erectile dysfunction. Can also treat symptoms such as pulmonary hypertension (a type of pulmonary hypertension).

The tablets are supplied in doses of 25 milligrams (mg), 50 mg or 100 mg.

Some of the benefits of taking sildenafil for erectile dysfunction are:

Immediate effect: About 30 minutes after taking the pill, it begins to work.

Research: clinical studies and research Reliable sources have confirmed its effectiveness.

Long-lasting effect: the effect lasts up to 4 hours.

Side effects: Serious side effects are rare, but can include allergic reactions and heart problems.

Some of the disadvantages are:

Short-term use: This may only be a short-term option, as 20-50% of people taking sildenafil take it temporarily.

Unsuitable for certain health conditions: According to a previous review from 2012, it may not be suitable for people with certain chronic conditions such as multiple sclerosis.

Drug interactions: May interact with other medications, such as heart disease and high blood pressure medications.

Preference: According to a 2017 study, both drugs are equally effective, but people seem to prefer the alternative drug tadalafil.

VIDALISTA (Tadalafil - Cialis)

Vidalista 60 Tadalafil works by increasing blood flow to the penis. Doctors also use this drug to treat high blood pressure in the lungs and benign prostatic hyperplasia. For erectile dysfunction, people take it as an oral tablet.

Some of the benefits of tadalafil include:

Longest lasting: This is the longest lasting PDE5 drug for erectile dysfunction, usually lasting up to 36 hours, but some reports suggest it can last up to 72 hours.

Long-term use: Low doses (2.5-5mg) can be taken once a day, which can be a long-term solution.

Daily use: People who engage in regular sexual activity may prefer to take tablets daily.

Increased confidence: Studies show that people who take tadalafil are sexually safer than those who take it.

However, the disadvantages are as follows.

Cost: Daily intake can be expensive.

Hidden Causes of Erectile Dysfunction: Long-term use may interfere with or delay treatment of potentially psychological root causes of erectile dysfunction.

Drug interactions: Tadalafil can interact with several types of medications, including common blood pressure medications.

Avana (Avanafil - Stendra)

Avana 100 Avanafil is another PDE5 drug. It works like any other medicine in its class by increasing blood flow to the penis.

Some of the benefits of avanafil are:

Immediate effect: Avanafil can start working 15 minutes after taking the medicine.

Safety: Studies have shown that avanafil is a safe and effective treatment for erectile dysfunction.

Duration: The effect can last up to 6 hours.

Popular with older and younger people: According to an early 2014 study, older and younger people preferred to take avanafil over other PDE5 medications because of their faster effects.

However, the major drawback of this drug is that it is more expensive than other PDE5 drugs because it is not currently available as a generic drug.

Vilitra (Vardenafil -Levitra)

Vilitra 60 (Vardenafil), like other PDE5 drugs for erectile dysfunction, works by increasing blood flow to the penis.

Some of the benefits of vardenafil include clinical research finding it effective. And unlike avanafil, vardenafil is available in a cheaper, more general form.

The downside is that the drug can take a relatively long time to start working-one should take it one hour before sexual activity. Also, vardenafil has no unique advantages over tadalafil or sildenafil.

How Do Erectile Dysfunction Drugs Work?

Research Trusted Source suggests that erectile dysfunction medications are safe and effective when taken under the supervision of a doctor.

Results may vary from individual to individual, but a 2021 review at the Pharmacology Frontier found that sildenafil 50 mg and 100 mg tablets were more effective than placebo. However, there is not yet sufficient data to compare tablets with different PDE5 inhibitors.

How to take erectile dysfunction drug?

Erectile dysfunction medications are usually taken about an hour before sex. However, the instructions may vary from drug to drug.

Some tablets need to be taken with food, while others need to be taken on an empty stomach.

You should always follow the instructions before taking prescription drugs.

What are the common side effects of Ed pills?

  • Flushing
  • Headache
  • Indigestion
  • Visual changes, such as a blue tinge to vision, sensitivity to light, or blurred vision
  • Stuffy or runny nose
  • Back pain
  • a stuffy or runny nose
  • hot flashes
  • muscle aches
  • Nausea